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JAMA. 1927;89(12):968. doi:10.1001/jama.1927.02690120044016.
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Calcium therapy has acquired a new interest in medicine along with the growing knowledge of the parts that the element may play in a variety of physiologic functions. These are no longer restricted to the building of the inorganic structure of the bones—a feature in which calcium is the most conspicuous element and is involved to the extent of several pounds in the adult person. Calcium has also become associated in as yet vaguely understood ways with the regulation of nervous, muscular and glandular activities, and in the coagulation of the blood; and it is believed to have some relations to variations in the permeability of the blood vessels and cells in such phenomena as transudation, the genesis of edema, and the appearance of urticarias.1

According to Sherman, the average calcium requirement of an adult person daily is about 0.5 Gm. As comparatively few common foods yield the element


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