Study concept and design: Patel, Roback, Easley, Josephson.
Acquisition, analysis, or interpretation of data: Patel, Knezevic, Shenvi, Hinkes, Keene, Roback, Easley, Josephson.
Drafting of the manuscript: Patel, Shenvi, Roback, Easley, Josephson.
Critical revision of the manuscript for important intellectual content: Knezevic, Shenvi, Hinkes, Keene, Roback, Easley, Josephson.
Statistical analysis: Patel, Knezevic, Shenvi, Roback, Easley, Josephson.
Obtained funding: Patel, Roback, Josephson.
Administrative, technical, or material support: Josephson.
Study supervision: Roback, Easley, Josephson.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: This work was supported by the National Institutes of Health. The National Heart, Lung, and Blood Institute provided funding for the parent study under award number P01 HL086773. The National Center for Advancing Translational Sciences provided support for this study and for Dr Patel under award numbers UL1 TR000454 and KL2 TR000455. Dr Patel reports receipt of research support from the Emory Children’s Center for Clinical and Translational Research.
Role of the Sponsor/Funder: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the National Institutes of Health or the Department of Health and Human Services.
Additional Contributions: We would like to thank all of the families who volunteered to participate in this study; the following research nurses (all of whom received salary support for prospective data collection for this study): Jane Skvarich, BSN, MN (Department of Pathology, Emory University School of Medicine, Atlanta, Georgia), Katrina H. Grier, BSN (Northside Hospital, Atlanta, Georgia), and Janna M. Benston, BSN (Northside Hospital, Atlanta, Georgia); and the following individuals for their epidemiological and statistical input (no compensation received): Mitch Klein, PhD (Rollins School of Public Health, Emory University, Atlanta, Georgia), Amita Manatunga, PhD (Rollins School of Public Health, Emory University, Atlanta, Georgia), and Muna Qayed, MD, MSc (Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia).