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RECENT ADVANCES IN PERNICIOUS ANEMIA

JAMA. 1927;89(10):793-794. doi:10.1001/jama.1927.02690100055016.
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Recently The Journal1 referred to an address delivered in this country by Knud Faber,2 in which the well known Danish clinician reaffirmed that pernicious anemia may be caused by intestinal intoxication, that achylia gastrica favors this process, and that the source of the toxic material is elsewhere than in the intestine when pernicious anemia develops in the course of an acute septic disease. Whatever the cause, if protracted hemolysis supervenes, the hematogenic organs become exhausted. Wells ventured the suggestion that this exhaustion may be enhanced by toxic substances in the blood. Knowledge of the important work of Whipple and Robscheit-Robbins,3 Gibson and Howard,4 and others,5 seems to have been lost to the general medical reader along with other material on dietotherapy of anemia. The Journal comment, therefore, substantially summarized the general knowledge of pernicious anemia up to the time of publication.

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