0
ARTICLE |

PARATHYROID HORMONE AND THE CALCIFICATION OF FRACTURE CALLUS

EDWIN P. LEHMAN, M.D.; WARREN H. COLE, M.D.
JAMA. 1927;89(8):587-588. doi:10.1001/jama.1927.02690080019008.
Text Size: A A A
Published online

On the assumption that, because the injection of parathyroid extract increases the calcium in the blood stream, there will be more available calcium for deposit in fracture callus, have been based certain clinical trials of parathyroid extract in the treatment of delayed union of fractures. The occurrence of union after the use of the hormone has confused the issue. It is our belief that parathyroid extract is being widely used on the misapprehension that it is of such value.

A priori, parathyroid extract should not offer aid in hastening or inducing the deposit of calcium in the soft callus about fractures. Its action is to mobilize the fixed calcium in the body. Indirect evidence of this action is presented by the work of several investigators including Hunter and Aub,1 who found that calcium excretion in patients is rapidly increased parallel to an increase in the blood serum calcium on

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();