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H. E. Bowles, M.D.
JAMA. 1941;116(24):2668-2669. doi:10.1001/jama.1941.62820240001009.
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Since perforation of the uterus by a hydatidiform mole is an extremely rare condition, it is felt that the presentation of the following account is justified.

In both Lord's1 case in 1868 and Seitz's1 in 1904 the outcome was fatal. Then followed a series of cases in which treatment by supracervical hysterectomy was successful. One was reported each by Waldo2 in 1910, Harkness1 in 1921, Krellenstein3 in 1924, Mazet4 in 1926 and Kallinikoff5 in 1928. Kallinikoff's patient was a multipara under the age of 25, as was Johannson's6 patient in 1929, who died after hysterectomy. Bland's7 patient in 1927, a nullipara aged 30, died fourteen months after the original operation following exploration of a recurrent chorioepithelioma. The first operation was performed at a time when the hydatid mole was undergoing malignant change. Gizowski8 reported another patient with such a uterine


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