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March 10, 1934, Vol 102, No. 10 >
ARTICLE | March 10, 1934

ARGYRIA FROM USE OF SILVER PROTEIN PREPARATIONS

A. J. Patek, M.D.
JAMA. 1934;102(10):787. doi:10.1001/jama.1934.02750100053025.
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ABSTRACT

To the Editor:—  In view of the timely remarks emphasizing the lurking danger in the indiscriminate use of neosilvol, a colloidal silver preparation, in disorders of the upper respiratory tract, as recently reported in The Journal (January 20, p. 202) by H. K. Berkley of Los Angeles, I am constrained to add my experience with another equally widely used and advertised silver salt; viz., argyrol.My personal unfortunate experience with argyrol covers two cases and knowledge of a third. Briefly, the case of marked argyria is that of a spinster, aged 60, who has for years had argyrol in 10 per cent solution in her possession as a constant household remedy. This patient has been subject to frequent colds and at every such provocation has been in the habit of instilling a few drops of the silver solution in both nostrils. She now has the unmistakable and, of course, indelible

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