We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......


Frank Mayner, M.D.
JAMA. 1941;116(18):2015-2016. doi:10.1001/jama.1941.62820180003006b.
Text Size: A A A
Published online

Reports of deaths due entirely to transfusion of whole blood are fairly rare. Reports of deaths due entirely to transfusion of plasma are still more rare. I have been unable to find any report of a fatality due to plasma transfusion in the English literature between the years 1927 and 1940. The lack of such reports may be explained by the only too recent enthusiasm over and use of transfusions of plasma.

REPORT OF CASE  A boy aged 4 years entered the hospital on July 31, 1940 because of severe edema. He had been perfectly well until one week before entry, when he acquired a cold the only manifestation of which was a running nose. He did not have a cough, sore throat, rash, articular pains, dyspnea or pains in the chest. Four days before entry he had edema of the ankles which gradually became generalized. One day before entry


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.