There is no reason to criticize the author for an important defect in this book, since it is manifestly impossible for any one person to survey adequately the literature covering three years of intensive investigation in the field. The material included is sound, attractively presented and judiciously evaluated. Nevertheless it is not a complete review, a fact which the author acknowledges in the preface to the fourth edition. The last chapter, on endocrine interrelationships, is especially inadequate, since it largely disregards the many developments of the past five years in what has come to be designated psychosomatic relations or psychobiology. The bibliography for the chapter on the parathyroid glands should be revised more completely, as it apparently contains many items no longer referred to in the text. The book is less extensive than the third edition by nearly thirty pages but in general follows the same style and arrangement.