This brochure is of interest to students and teachers in experimental pharmacology. The exercises outlined are concisely stated and of sufficient number to demonstrate the fundamental facts concerning the mechanism of drug action. A few of the exercises are gargantuan; for example, to demonstrate the action of carbon monoxide, the author uses an automobile and with a garden hose conducts the gas into a box where the dog is incarcerated. Such an experiment well demonstrates some automobile adventures, but most laboratory workers would find a much simpler method of demonstrating the action of carbon monoxide or of illuminating gases. The student who sees the exercises listed in this book demonstrated or who performs them himself has adequate opportunity to become well grounded in the fundamentals of pharmacology.