Study concept and design: Chawes, Bønnelykke, Stokholm, Bisgaard.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Chawes, Bønnelykke, Stokholm, Bisgaard.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Chawes, Stokholm, Rasmussen.
Obtained funding: Chawes, Bønnelykke, Stokholm, Vissing, Bisgaard.
Administrative, technical, or material support: Chawes, Bønnelykke, Stokholm, Heickendorff, Brix, Bisgaard.
Study supervision: Chawes, Bønnelykke, Stokholm, Bisgaard.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Bisgaard reports receiving consulting fees from Chiesi. No other disclosures were reported.
Funding/Support: The Copenhagen Prospective Study on Asthma in Childhood (COPSAC) is funded by private and public research funds that are all listed on http://www.copsac.com. The Lundbeck Foundation, Danish State Budget, Danish Council for Strategic Research, Danish Council for Independent Research, and the Capital Region Research Foundation have provided core support for COPSAC.
Role of the Funder/Sponsor: The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.
Additional Information: The COPSAC biobank is publicly available at the Danish National Biobank (http://www.biobankdenmark.dk) and data will become available in the Danish Data Archive (https://www.sa.dk/).
Additional Contributions: We thank the children and families of the COPSAC2010 cohort study for all their support and commitment. We also thank the COPSAC research team for their efforts.