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Comment & Response |

Epinephrine Administration and Pediatric In-Hospital Cardiac Arrest

Alison Poulton, MD, MA, MBBChir1; Frank Chen, MBChB2; Ralph Nanan, DrMedHabil, FRACP1
[+] Author Affiliations
1Sydney Medical School Nepean, University of Sydney, Sydney, Australia
2Nepean Hospital, Sydney, Australia
JAMA. 2016;315(4):416-417. doi:10.1001/jama.2015.16449.
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To the Editor The study by Dr Andersen and colleagues1 found an association between delayed administration of epinephrine and poorer survival rates after in-hospital pediatric cardiac arrest.

There are at least 3 possible scenarios for delivering epinephrine: the patient might already have a functioning cannula or central line, venous access might be attempted during resuscitation, or epinephrine might be delivered by intraosseous injection. Epinephrine can be given quickly and reliably by intraosseous injection, but clinicians could preferentially attempt intravenous administration first.

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January 26, 2016
Lars W. Andersen, MD; Katherine M. Berg, MD; Michael W. Donnino, MD
1Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark
2Division of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
3Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
JAMA. 2016;315(4):417. doi:10.1001/jama.2015.16464.
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