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Louis Tulipan, M.D.
JAMA. 1941;116(14):1518-1519. doi:10.1001/jama.1941.62820140004007c.
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Literature on intertrigo, a distressingly common disease, is exceedingly scarce, particularly in the United States. Therefore, in order to make clear the logic of the proposed therapy, I shall briefly review its known causes and symptoms.

Intertrigo results from friction of apposing surfaces of the skin and occurs in the following locations: the groins, the intergluteal folds, the inner sides of the thighs, the axillas, the submammary folds of women, the hypogastric fold, the retroauricular fold and the folds of the neck, groins and buttocks of newborn infants.

Additional etiologic factors are obesity, excessive perspiration, heat, fungous or bacterial infection and regional secretions such as urine, feces, serous or purulent discharges, vaginal discharges and menstrual fluid.

The condition may manifest itself on the skin as a mild erythema, a vesicular or papular eruption similar to that of lichen tropicus (prickly heat) or as a vesicular, papular, or lichenified eczema which


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