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David I. Macht, M.D.
JAMA. 1934;102(7):557-558. doi:10.1001/jama.1934.02750070055025.
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To the Editor:—  I have read with great interest the admirable address of Prof. C. D. Leake on "The Rôle of Pharmacology in the Development of Ideal Anesthesia," published in The Journal, January 6. To me, one of the most interesting parts of this paper is the first footnote, in which Dr. Leake suggests the coining of a new word, "biochemorphic." Devotees of the basic medical sciences, and particularly of pharmacology, should be grateful to Dr. Leake for emphasizing one of the most important aspects of pharmacology—in my opinion, the most important aspect of that science — namely, the relationship between the chemical constitution or structure (including physical properties) and the physiologic or biologic effects of drugs. This is a field in which I have been active in a modest way, and in connection with my work I have often felt the greatest need of an adequate term, substantive and


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