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REPEATED ACIDOSIS AND COMA IN JUVENILE DIABETES

THOMAS A. CLAWSON Jr., M.D.; GEORGE A. HARROP Jr., M.D.
JAMA. 1927;89(1):23-24. doi:10.1001/jama.1927.02690010023008.
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The eventual prognosis in patients with juvenile diabetes has aroused great interest recently, since it has become quite evident that modern methods of treatment are of especial value in this type of the disease. It has been frequently emphasized that diabetes in childhood and in youth is usually uncomplicated by any of the numerous extra factors that may be present in later life. Diabetic children in the absence of severe infection usually respond very readily to dietary measures and to insulin, and severe acidosis or coma, in general, is quite as amenable to treatment as it is in older patients in whom diabetes is generally considered to be less severe. Recent articles by prominent American students of the disease (Joslin, Geyelin) indicate that the experience gained in the study of large series

of cases since the introduction of insulin gives just cause for a considerable measure of optimism. In sharp

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