Study concept and design: Kitzman, Morgan, Hundley, Nicklas.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Kitzman, Brubaker, Morgan, Haykowsky, Eggebeen.
Critical revision of the manuscript for important intellectual content: Kitzman, Brubaker, Haykowsky, Hundley, Kraus, Eggebeen, Nicklas.
Statistical analysis: Kitzman, Morgan, Eggebeen.
Obtained funding: Kitzman, Nicklas.
Administrative, technical, or material support: Kitzman, Brubaker, Hundley, Eggebeen, Nicklas.
Study supervision: Kitzman, Brubaker, Eggebeen, Nicklas.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Kitzman reports receiving personal fees from Icon, Relypsa, Abbvie, Regeneron, GlaxoSmithKline, Merck, Forest Labs, and Corvia Medical; receiving grant support from Novartis; and owning stock in Gilead Sciences and stock options in Relypsa. No other disclosures were reported.
Funding/Sponsor: This study was supported by research grants R01AG18915, P30AG021332, R01HL093713, and R01AG020583 from the National Institutes of Health. Also supported in part by the Kermit Glenn Phillips II Chair in Cardiovascular Medicine at Wake Forest School of Medicine (Dr Kitzman) and the Mortiz Chair in Geriatric Nursing Research in the College of Nursing and Health Innovation at The University of Texas at Arlington (Dr Haykowsky).
Role of the Funder/Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.