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ARTICLE |

A SIMPLIFIED CITRATE-DEXTROSE BLOOD PRESERVATIVE

FRANK E. BARTON, M.D.
JAMA. 1941;116(12):1196-1197. doi:10.1001/jama.1941.02820120010002.
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In the Oct. 14, 1939 issue of The Journal the Transfusion Service of the Massachusetts Memorial Hospitals, Boston, reported on "The Use of Placental Blood for Transfusion."1 This article emphasized among other things the advantage obtained by the addition of dextrose to the preservative. We reported that the addition of dextrose retarded hemolysis from fourteen and four-tenths days to twenty-two and threetenths days. This same paper stated that we were confident a series of blood specimens then being studied would show an even more delayed hemolysis. It is on this series of 250 blood specimens that we are now reporting.

The Rous and Turner2 solution consisting of dextrose, citrate and blood, as described by Robertson,3 was efficacious in delaying hemolysis. There were two outstanding disadvantages in their technic: (1) the large amount of preservative that was required; (2) the concentration of sodium citrate in the mixture, which

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