A white man, aged 22, an American, married and father of two children, appeared at the Ohio State University, State Street Dispensary, Dec. 14, 1926, complaining of weakness and shortness of breath. He was told to report to the University Hospital the next day for study and diagnosis, where he was assigned to the general medical service of Dean J. H. J. Upham and to the immediate care of Dr. George I. Nelson, internist. We are indebted to both of these physicians for permission to abstract such parts of the history of the case as are taken from the hospital records made during the patient's six months' stay in the University Hospital.
When his history was taken he stated that about August 15 he first noticed a sallowness of the skin. About two months later, weakness, palpitation, dizziness and shortness of breath on exertion appeared. Headaches began about November 13,