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Frank A. Simon, M.D.; Francis M. Rackemann, M.D.
JAMA. 1934;102(2):127-128. doi:10.1001/jama.1934.62750020002009b.
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Eczema due to contact with various substances in the environment is a well recognized condition to which the literature contains many references.1 The diagnosis of the cause in the individual patient is not easy, and the case reported here demonstrates the need of prolonged study and observation and the good results that will reward the effort. It also shows how widely distributed the cause of trouble may be.

REPORT OF CASE  A man, aged 29, developed a small area of eczema on the left wrist in November, 1928. Similar lesions soon appeared on the dorsal aspect of both hands and fingers. They were of the acute, vesicular type, with oozing and thickening of the skin. It is of interest to note that the lesions made their first appearance at the site of an abrasion caused by a stiffly starched cuff. Various local applications had no apparent effect on the course


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