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Comment & Response |

Medical Use of Cannabinoids

Igor Grant, MD1
[+] Author Affiliations
1University of California Center for Medicinal Cannabis Research, University of California San Diego, La Jolla
JAMA. 2015;314(16):1750-1751. doi:10.1001/jama.2015.11429.
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To the Editor Dr Whiting and colleagues presented a systematic review of medical cannabinoids.1 The University of California Center for Medicinal Cannabis Research has conducted 5 placebo-controlled clinical trials with smoked or inhaled cannabis for neuropathic pain, representing, to my knowledge, the only studies approved by the US Department of Health and Human Services to be conducted in the United States during the past 2 decades.

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October 27, 2015
Penny Whiting, PhD; Robert Wolff, MD
1University of Bristol, Bristol, England
2Kleijnen Systematic Reviews, York, England
JAMA. 2015;314(16):1751-1752. doi:10.1001/jama.2015.11447.
June 23, 2015
Penny F. Whiting, PhD; Robert F. Wolff, MD; Sohan Deshpande, MSc; Marcello Di Nisio, PhD; Steven Duffy, PgD; Adrian V. Hernandez, MD, PhD; J. Christiaan Keurentjes, MD, PhD; Shona Lang, PhD; Kate Misso, MSc; Steve Ryder, MSc; Simone Schmidlkofer, MSc; Marie Westwood, PhD; Jos Kleijnen, MD, PhD
1School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom2The National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West at University Hospitals, Bristol NHS Foundation Trust, Bristol, United Kingdom3Kleijnen Systematic Reviews Ltd, Escrick, York, United Kingdom
3Kleijnen Systematic Reviews Ltd, Escrick, York, United Kingdom
4Department of Medical, Oral, and Biotechnological Sciences, University “G. D'Annunzio” of Chieti-Pescara, Chieti, Italy5Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
6Medical School, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru7Health Outcomes and Clinical Epidemiology Section, Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio
8Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands
9Institut für Epidemiologie und kongenitale Erkrankungen, Cepicon GmbH, Hamburg, Germany
3Kleijnen Systematic Reviews Ltd, Escrick, York, United Kingdom10School for Public Health and Primary Care (CAPHRI), Maastricht University, Maastricht, the Netherlands
JAMA. 2015;313(24):2456-2473. doi:10.1001/jama.2015.6358.
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