The fact that this book appears now in the fifth edition in fifteen years attests its popularity with medical students, for whom it was written. Features that have made it popular with them are the clearness of the text and the abundance of the illustrations. There are 594 figures with 4 plates. More than half were made especially for this work and many are based on photographs. The chapters on histologic technic and on directions for laboratory work have made it especially useful in the class room. In this edition the section on the function of the hypophysis has been rewritten and there has been added a new view of bone growth based on the work of Policard and Leriche ascribing a new rôle to osteoblasts, osteoclasts and bone cells. Progress in other fields has been noted mainly by footnotes to the text.