This medical annual is now in its fifty-first year. It begins with a review of a year's work in therapy. It provides incidentally an obituary notice of Dr. Carey F. Coombs, who died this year and who was for fourteen years editor of this publication. The volume is contributed to by a great number of writers selected by the editors, all of them British and all of them well known for work in the fields to which they contribute. It has a fine index and is fully illustrated with many plates, some of them in colors, most of them borrowed from current periodicals. The book constitutes a good reference work, particularly for those who want the latest word on any medical subject.