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Hideyo Noguchi, M.D.
JAMA. 1927;88(9):667. doi:10.1001/jama.1927.02680350051029.
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To the Editor:  —In an article entitled "Abnormal Bacterial Flagella in Cultures: Their Resemblance to Spirochetes" (The Journal, May 1, 1926, p. 1327) I described and pictured various types of detached overgrown bacterial flagella as seen by dark field illumination. This type of illumination brings out forms of extreme thinness not visible by ordinary illumination, the forms that are most readily confused with spirochetes. Since the dark field microscope is extensively used for research on spirochetes, I was concerned chiefly with the appearance of the flagella by dark field, and I omitted to mention that the subject had previously been investigated by bright field and staining methods. I wish to call the attention of those interested in this problem to a paper by Dr. Laura Florence (J. Bacteriol. 6:371 [July] 1921) in which the work on abnormal bacterial flagella as studied by bright field methods is reviewed and extended.


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