0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

HETEROLOGOUS SCARLET FEVER

J. D. TRASK, M.D.; F. G. BLAKE, M.D.
JAMA. 1933;101(10):753-756. doi:10.1001/jama.1933.02740350011003.
Text Size: A A A
Published online

In 1924 we1 described the presence of scarlet fever toxin in the blood of certain patients with scarlet fever. This observation was confirmed by Cooke.2 The toxin was demonstrated by the intracutaneous injection of patients' serum into a group of human volunteers composed of four persons whose serum failed to blanch the rash in scarlet fever and of four whose serum blanched the rash. Those whose serum failed to blanch the rash served as test subjects and the other four as controls. Subsequently, Dick tests were done on the group of volunteers. The test subjects gave positive reactions to the Dick test, and the controls, negative reactions. The reactions elicited by the serums and the Dick tests were similar. The toxin in the patients' serums was shown to be neutralizable both by natural human antitoxin and by artificially produced horse antitoxin. Heterogenicity among the toxins was not observed,

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();