This volume is a medical monograph that deals with the subjects indicated in the title. It therefore is a digest of the literature rather than a record of the authors' researches. The text is up to date, is well written, and should be of value to those interested in the subject. It is particularly fitting that the authors are the discoverers of the physiologic action that has raised ephedrine from obscurity to its place of importance in medicine. An excellent bibliography adds to the value of the volume.