F. M. Pottenger Jr., M.D.
JAMA. 1930;95(20):1503-1504. doi:10.1001/jama.1930.27210200001011.
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Hypodermoclysis and intravenous therapy are at present administered by two general methods; namely, by means of the Kelly bottle and by the inverted flask as a reservoir with the necessary connections. Neither method gives complete satisfaction as used at present. Use of the Kelly bottle necessitates the transfer of sterile fluid from one container to another, offering an opportunity for contamination. To set up the inverted flask with the clamp and plate that are universally employed to maintain the stopper in position requires about five minutes. The metal connection corrodes under sterilization and use and the rubber ordinarily used soon deteriorates when subjected to repeated heat sterilizations.

In an effort to overcome these difficulties, two rubber connectors were developed. These connectors slip over the necks of flasks or bottles in the same manner as nursing nipples and are made in sizes to suit the various requirements. By using these, an


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