Study concept and design: Chew, Grodstein.
Acquisition, analysis, or interpretation of data: Chew, Clemons, Agrón, Launer, Bernstein.
Drafting of the manuscript: Chew, Agrón.
Critical revision of the manuscript for important intellectual content: Chew, Clemons, Agrón, Launer, Grodstein, Bernstein.
Statistical analysis: Clemons, Agrón, Launer.
Obtained funding: Chew, Clemons.
Administrative, technical, or material support: Chew, Clemons, Grodstein.
Study supervision: Chew.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Bernstein reports serving as a consultant for Kemin Health, Kalsec, DSM, and ScienceBased Health. No additional disclosures were reported.
Funding/Support: This study was sponsored by the NIH; by the intramural program funds and contracts from the National Eye Institute (NEI)/NIH, Department of Health and Human Services, contract HHS-N-260-2005-00007-C. ADB and contract N01-EY-5-0007. Funds were generously contributed to these contracts by the following NIH institutes: Office of Dietary Supplements (ODS), National Center for Complementary and Alternative Medicine (NCCAM), National Institute on Aging (NIA), National Heart, Lung, and Blood Institute (NHLBI), and National Institute of Neurological Disorders and Stroke (NINDS).
Role of the Funder/Sponsor: Dr Chew is responsible for the management, analysis, and interpretation of the data as well as the preparation, review, and approval of the manuscript. The decision to submit the manuscript for publication was also determined by Dr Chew, a staff member of the funding agency.