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JAMA Clinical Guidelines Synopsis |

Prostate Cancer Screening

Scott E. Eggener, MD1; Adam S. Cifu, MD2; Chadi Nabhan, MD3
[+] Author Affiliations
1Section of Urology, Department of Surgery, University of Chicago, Chicago, Illinois
2Section of General Internal Medicine, Department of Medicine, University of Chicago
3Section of Hematology and Oncology, Department of Medicine, University of Chicago
JAMA. 2015;314(8):825-826. doi:10.1001/jama.2015.8033.
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This JAMA Clinical Guidelines Synopsis summarizes the US Preventive Services Task Force’s (2012) and American Urological Association’s (2013) clinical practice guidelines for prostate cancer screening.

Box Section Ref ID

Guideline title Screening for Prostate Cancer

Developers US Preventive Services Task Force (USPSTF), American Urological Association (AUA)

Release dates May 2012 (USPSTF), April 2013 (AUA)

Prior versions 2008 (USPSTF), 2009 Best Practice Statement (AUA)

Funding sources Agency for Healthcare Research and Quality (AHRQ), AUA

Target populations USPSTF: men considering prostate-specific antigen (PSA) screening for prostate cancer; AUA: asymptomatic men at average risk of developing prostate cancer

Major recommendations The USPSTF recommends against PSA-based screening for prostate cancer due to moderate or high certainty that the test has no net benefit or the harms outweigh the benefits (grade D). The AUA recommends shared decision making for men aged 55 to 69 years; for men electing to be screened, an interval of 2 years or more may be preferable to annual screening. The AUA recommends against PSA screening in men younger than 40 years, against routine screening between ages 40 and 54 years for men at average risk, and against routine screening in men older than 70 years or any man with less than a 10- to 15-year life expectancy.

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