The author has reviewed much of the voluminous literature stimulated by the discovery of insulin and has performed a service by classifying these contributions simply and clearly. This is probably the most complete review of the subject that has appeared, and it will doubtless remain in France a basic review of the literature on insulin. Clinical researches and observations and experimental studies on normal and depancreatized animals by the author and his colleagues are included. The book is divided into three parts: the discovery, manufacture and nature of insulin; its physiologic properties and mode of action, and its therapeutic utilization. A detailed table of contents is serviceable because of the clear arrangement of material under numerous subtitles; an index is lacking.