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ARTICLE |

Council on Pharmacy and Chemistry

JAMA. 1933;100(17):1331-1338. doi:10.1001/jama.1933.02740170029010.
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Doisy, E. A.; Veler, C. D., and Thayer, S.: Proc. XIII Internat. Physiol. Cong., Am. J. Physiol. 90:329 ( (Oct.) ) 1929
J. Biol. Chem. 86:499 ( (April) ) 1930.
Doisy, Thayer and Veler: Proc. Soc. Exper. Biol. & Med. 27:417 ( (Feb.) ) 1930.
Veler, Thayer and Doisy: J. Biol. Chem. 87:357 ( (June) ) 1930.
Schwitalla, A. M.: J. A. M. A. 94:1523 ( (May 10) ) 1930
Bull. St. Louis Univ. 27, (July) , 1931
 Theelin—and the Technic of Introduction of New Drugs, editorial , J. A. M. A. 97: 1541 ( (Nov. 21) ) 1931.
Doisy, E. A.; Thayer, S. A.; Levin, L., and Curtis, J. M.: Proc. Soc. Exper. Biol. & Med. 28:88 ( (Oct.) ) 1930.
Doisy and Thayer: J. Biol. Chem. 91:641 ( (May) ) 1931.
Thayer, Levin and Doisy, J. Biol. Chem. 193191 (May) , p. 655
 Theelin and Theelol, editorial , J. A. M. A. 97:33 ( (July 4) ) 1931.
Allen, Edgar, and Doisy, E. A.: J. A. M. A. 81:819 ( (Sept. 8) ) 1923.
Allen, Edgar: J. A. M. A. 97: 1189 ( (Oct. 24) ) 1931.
Fröhlich, A.: Wien. klin. Rundschau 15: 1901
Parkes, A. S.: Internal Secretion of the Ovary , London, 1929
Erdheim, J., and Stumme, E.: Beitr. z. path. Anat. u. z. allg. Path. 46: 1, 1909.
Cushing, Harvey: The Pituitary Body and Its Disorders , Philadelphia, 1912.
Evans, H. M.: Harvey Lectures 19:212, 1923-1924.
Smith, P. E.: Anat. Rec. 32:221, 1926
Proc. Soc. Exper. Biol. & Med. 24:131 ( (Nov.) ) 1926
337 (Jan.) 1927
Am. J. Physiol. 80: 114 ( (March) ) 1927
81:20 (June) 1927.
Smith, P. E., and Engle, E. T.: Proc. Soc. Exper. Biol. & Med. 24:561 ( (March) ) 1927
Anat. Rec. 35:22 ( (March) ) 1927
Am. J. Anat. 40: 159 ( (Nov.) ) 1927.
Zondek, Bernhard: Klin. Wchnschr. 6:135 ( (Jan. 15) ) 1927
Link to Article[[XSLOpenURL/10.1007/BF01736919]]
Med. Klin. 23:463 ( (March 31) ) 1927.
Zondek, Bernhard, and Aschheim, Selmar: Klin. Wchnschr. 6:248 ( (Feb. 5) ) 1927
Link to Article[[XSLOpenURL/10.1007/BF01710709]]
Arch. f. Gynäk. 130: 1, 1927
Link to Article[[XSLOpenURL/10.1007/BF01736546]]
Klin. Wchnschr. 6: 1322 ( (July 9) ) 1927.
Hartman, C. G.; Firor, W. M., and Ceiling, E. M. K.: Am. J. Physiol. 95:662 ( (Dec.) ) 1930.
Saiki, S.: Am. J. Physiol. 100:8 ( (March) ) 1932.
Corner, G. W.: Am. J. Physiol. 95:43 ( (Oct.) ) 1930.
Riddle, O.; Bates, R. W., and Dykshorn, S. W.: Proc. Soc. Exper. Biol. & Med. 29:1211 ( (June) ) 1932.
Fevold, H. L.; Hisaw, F. L., and Leonard, S. L.: Am. J. Physiol. 97: 291 ( (May) ) 1931.
Engle, E. T.: Sex and Internal Secretions , edited by Edgar Allen, Baltimore, Williams and Wilkins Company, 1932,  chapter 16 
Proc. Soc. Exper. Biol. & Med. 29: 1224 ( (June) ) 1932.
Aschheim, Selmar, and Zondek, Bernhard: Klin. Wchnschr. 7: 1404 ( (July 22) ) 1928.
Engle, E. T.: J. A. M. A. 93:276 ( (July 27) ) 1929.
Reichert, F. L.; Pencharz, R. I.; Simpson, M. E.; Meyer, K., and Evans, H. M.: Proc. Soc. Exper. Biol. & Med. 28:843 ( (May) ) 1931.
Evans, H. M.; Meyer, K., and Simpson, M. E.: Am. J. Physiol. 100: 141, 1932.
Wiesner, B. P., and Crew, F. A. E.: Proc. Roy. Soc. Edinburgh 50:79, 1929-1930.
Wiesner, B. P.: Edinburgh M. J. 37:73 ( (Feb.) ) 1930.
Collip, J. B.: Canad. M. A. J. 22:215 ( (Feb.) ), 761 (June)
23: 631 (Nov.) 1930.
Aschheim, Selmar, and Zondek, Bernhard: Klin. Wchnschr. 7:8 ( (Jan. 1) ) 1928.
Aschheim, Selmar: Am. J. Obst. & Gynec. 19:335 ( (March) ) 1930.
Siddall, A. C.: J. A. M. A. 90: 380 ( (Feb. 4) )
Link to Article[[XSLOpenURL/10.1001/jama.1928.02690320042012]]
91: 779 (Sept. 15) 1928.
Friedman, M. H.: Am. J. Physiol. 90:617, 1929.
Friedman, M. H., and Lapham, M. E.: Am. J. Obst. & Gynec. 21:405, 1931.
Mazer, C., and Hoffman, J., Am. J. Obst. & Gynec. 17:186, 1929
18: 48:1929
J. A. M. A. 96:19 ( (Jan. 3) ) 1931.
Kelly, G. L.: J. A. M. A. 100:1010 ( (April 1) ) 1933.
Frank, R. T.; Frank, M. L.; Gustavson, R. G., and Weyerts, W. W.: J. A. M. A. 85:510 ( (Aug. 15) ) 1925.
Frank, R. T., and Goldberger, M. A., J. A. M. A. 87:719 ( (Sept. 4) ) 1926
90:106 (Jan. 14) 1928
94: 1197 (April 19) 1930.
Frank, R. T.; Goldberger, M. A., and Spielman, F.: Proc. Soc. Exper. Biol. & Med. 28:999, 1931.
Frank, R. T.: J. A. M. A. : 97:1855 ( (Dec. 19) ) 1931.
Fluhmann, C. F.: J. A. M. A. 92:1744 ( (May 25) ) 1929
93:672 (Aug. 31), 1136 (Oct. 12) 1929
Am. J. Obst. & Gynec. 20:1 ( (July) ) 1930
Endocrinology 15:177 ( (May-June) ) 1931
Proc. Soc. Exper. Biol. & Med. 29:1193 ( (June) ) 1932.
Kurzrok, R.: Endocrinology 16:361 ( (July-Aug.) ) 1932.
Eberson, F., and Silverberg, M. H.: J. A. M. A. 96: 2176 ( (June 27) ) 1931.
Mazer, C., and Goldstein, L.: Clinical Endocrinology of the Female , Philadelphia, 1932.
Soule, S. D.: Am. J. Obst. & Gynec. 23:708 ( (May) ) 1932.
Fee, A. R., and Parkes, A. S.: J. Physiol. 67: 383, 1929.
Friedman, M. H.: Am. J. Physiol. 99:332 ( (Jan.) ) 1932.
Hofbauer, J.: Surg., Gynec. & Obst. 52:222 ( (Feb.) ) 1931.
Smith, P. E., and White, W. E.: J. A. M. A. 97: 1861 ( (Dec. 19) ) 1931.
Link to Article[[XSLOpenURL/10.1001/jama.1931.02730250019007]]
Corner; Riddle, Bates and Dykshorn.13
Zondek, Bernhard: Zentralbl. f. Gynäk. 53:834 ( (April 6) ) 1929
abst. J. A. M. A. 93:247 [ (July 20) ] 1929
Smith, P. E.: Anat. Rec. 32:221, 1926.
Parkes, A. S.: Internal Secretion of the Ovary , London, 1929.
Frank, R. T.: Colorado Med. 21:123 ( (May) ) 1924.
Butenandt, A.: Deutsche med. Wchnschr. 55: 2171 ( (Dec. 27) ) 1929.
Link to Article[[XSLOpenURL/10.1055/s-0028-1127488]]
Frank, R. T.: J. A. M. A. 78: 181 ( (Jan. 21) ) 1922.
Link to Article[[XSLOpenURL/10.1001/jama.1922.02640560023009]]
Allen, Edgar, and Doisy, E. A.: 81: 819 (Sept. 8) 1923.
Frank, R. T., and Gustavson, R. G.: J. A. M. A. 84:1715 ( (June 6) ) 1925.
Link to Article[[XSLOpenURL/10.1001/jama.1925.02660490007004]]
Allen, Edgar; Pratt, J. P., and Doisy, E. A.: J. A. M. A. 85:399 ( (Aug. 8) ) 1925.
Link to Article[[XSLOpenURL/10.1001/jama.1925.02670060001001]]
Allen, Edgar; Pratt, J. P.; Newell, Q. U., and Bland, L. J.: Am. J. Physiol. 92: 127 ( (Feb.) ) 1930.
Frank, R. T.: J. A. M. A. 81:1134 ( (Sept. 29) ) 1923.
Link to Article[[XSLOpenURL/10.1001/jama.1923.02650130071028]]
Jeffcoate, T. N. A.: J. Obst. & Gynec. Brit. Emp. 39:67, 1932.
Frank, R. T., and Goldberger, M. A.: Proc Soc. Exper. Biol. & Med. 25: 476, 1928.
Laqueur, E.; Digemanse, E.; Hart, P. C., and de Jongh, S. E.: Klin. Wchnschr. 6: 1859, 1927.
Mazer, C., and Goldstein, L.: Clinical Endocrinology of the Female , Philadelphia, 1932.
Doisy, E. A.: Sex and Internal Secretions , Baltimore, 1932,  chapter 10. 
Cook, J. W.; Dodds, E. C., and Hewett, C. L.: Nature 131:56 ( (Jan. 14) ) 1933.
Cook, J. W., and Dodds, E. C.: Nature 131205 ( (Feb. 11) ) 1933.
Allen, Edgar, and Doisy, E. A.: Am. J. Physiol. 69: 577 ( (Aug.) ) 1924.
Allen, Edgar: Contrib. to Embryol. , Carnegie Inst. Wash., Publ. No. 380, 19: 1, 1927.
Hartman, Firor and Geiling; Saiki.12
Kunde, Margarete, M.; D'Amour, F. E.; Carlson, A. J., and Gustavson, R. G.: Am. J. Physiol. 95: 630 ( (Dec.) ) 1930.
Turner, C. W., and others: Anat. Rec. 53:227 ( (July 25) ) 1932.
Kunde, D'Amour, Gustavson and Carlson: Proc. Soc. Exper. Biol. & Med. 27:122 ( (Nov.) ) 1930.
Spencer, J.; Gustavson, R. G., and D'Amour, F. E., Proc. Soc. Exper. Biol. & Med. (Nov.) 28:500, 1931.
Wade, N. J., and Doisy, E. A., Proc. Soc. Exper. Biol. & Med. (Nov.) 28: 714, 1931.
Katzman, P. A.: Proc. Soc. Exper. Biol. & Med. 29: 700 ( (March) ) 1932.
Kelly, G. L.: Surg., Gynec. & Obst. 52:713 ( (March) ) 1931.
Levin, L.; Katzman, P. A., and Doisy, E. A.: Endocrinology 15:207 ( (May-June) ) 1931.
Witherspoon, J. T.: Proc. Soc. Exper. Biol. & Med. 29: 1063 ( (June) ) 1932.
Igataki; cited from Carlson, A. J.: J. A. M. A. 83: 1920 ( (Dec. 13) ) 1924.
Reynolds, S. R. M., and Allen, W. M.: Am. J. Physiol. 102: 39 ( (Oct.) ) 1932.
Novak, Emil, and Reynolds, S. R. M.: J. A. M. A. 99:1466 ( (Oct. 29) ) 1932.
Bourne and Burn: Lancet 2: 1020, 1928.
Allen and Wiles, cited from Marshall, F. H. A.: Brit. M. J. 2:232 ( (Aug. 6) ) 1932.
Smith, P. E.: Am. J. Physiol. 99:345 ( (Jan.) ) 1932.
Allen, W. M.: Am. J. Physiol. 100: 650 ( (May) ) 1932.
David, J. C.: J. Pharmacol. & Exper. Therap. 43: 1, 1931.
Birch, Carroll LeFleur: Proc. Soc. Exper. Biol. & Med. 28:752 ( (April) ) 1931
J. A. M. A. 97:244 ( (July 25) ) 1931
99: 1566 (Nov. 5) 1932.
Immamura: Acta Med. , Kaijo 12:249, 1929
 Follicular Antitoxin and the "Reynals Factor," Current Comment , J. A. M. A. 98: 323 [ (Jan. 23) ] 1932
Lacassagne, M. A.: Compt. rend. Acad. d. sc. 195: 630 ( (Oct. 10) ) 1932.
Allen, W. M., and Corner, G. W.: Proc. Soc. Exper. Biol. & Med. 27:403 ( (Feb.) ) 1930.
Allen, W. M.: Am. J. Physiol. 92:174 ( (Feb.) ) 1930.
Hisaw, F. L.: J. Exper. Zool. 42:411 ( (Oct.) ) 1925
Proc. Soc. Exper. Biol. & Med. 23:661 ( (May) ) 1926.
Hisaw, F. L.; Meyer, R. K., and Fevold, H. L.: Proc. Soc. Exper. Biol. & Med. 27:606 ( (March) ) 1930
(cited from Allen).5
Hisaw, F. L.: Sex and Internal Secretions , Baltimore, 1932,  chapter 11. 
Smith, G. V. S., and Smith, O. W.: J. A. M. A. 97:1857 ( (Dec. 19) ) 1931.
Hisaw, F. L.; Meyer, R. K., and Fevold, H. L.: Proc. Soc. Exper. Biol. & Med. 27: 400 ( (Feb.) ) 1930.
Meyer, R. K., and Allen, W. M.: Science 75:111 ( (Jan. 22) ) 1932.
Harris, R. G.: Science 76: 408 ( (Nov. 4) ) 1932.
Smith, P. E., and Engle, E. T.: Proc. Soc. Exper. Biol. & Med. 29:1225 ( (June) ) 1932.
Smith and Smith.57
Macht, D. D., and Stickels, A. E.: Proc. Soc. Exper. Biol. & Med. 27:427 ( (Feb.) ) 1930
28:801 (May) 1931.
Frank, R. T.; Goldberger, M. A., and Spielman, F.: Proc. Soc. Exper. Biol. & Med. 29: 1229 ( (June) ) 1932.
Mazer, C., and Ziserman, A. J.: M. J. & Rec. 135: 35 ( (Jan. 6) ) 1932.
Fee, A. R.; Marrian, G. F., and Parkes, A. S.: J. Physiol. 67: 377 ( (July 25) ) 1929.
Marshall, F. H. A., and Wood, W. A.: J. Physiol. 58: 74 ( (Oct.) ) 1923.
Hartman, C. G.: J. A. M. A. 97: 1863 ( (Dec. 19) ) 1931.
Corner, G. W.: J. A. M. A. 89: 1839 ( (Nov. 26) ) 1927.
Allen, Edgar; Doisy, E. A., and others: Am. J. Anat. 34: 133, 1924.
Coward, K. H., and Burn, J. H.: J. Physiol. 63: 270 ( (Aug. 8) ) 1927.
Burn, J. H.: Physiol. Rev. 10:146 ( (Jan.) ) 1930.
Burn, J. H., and Elphick, G. K.: Quart. J. Pharmacol. 5:192 ( (April-June) ) 1932.
Trevan: Proc. Roy. Soc., series B 101:481, 1927
Link to Article[[XSLOpenURL/10.1098/rspb.1927.0030]]
D'Amour, F. E., and Gustavson, R. G.: J. Pharmacol. & Exper. Therap. 40: 485, 1930.
Becker, T. J.; Mellish, C. N.; D'Amour, F. E., and Gustavson, R. G.: J. Pharmacol. & Exper. Therap. 43:693 ( (Dec.) ) 1931.
Marrian, G. F., and Parkes, A. S.: J. Physiol. 67:389, 1929.
Dodds, E. C.: Tr. Am. Gynec. Soc. 56: 134, 1931.
Pratt, J. P., and Allen, Edgar: J. A. M. A. 86:1964 ( (June 26) ) 1926.
Novak, Emil, J. A. M. A. 90:339 ( (Feb. 4) ) 1928.
King, J. T., Jr., and Patterson, Ellen, J. A. M. A. 91:1423 ( (Nov. 10) ) 1928.
 Council Report , KingJ. A. M. A. 91:1193 ( (Oct. 20) ) 1928.
Dodds, E. C., and Robertson, J. D.: Lancet 1:1390, 1930.
Campbell, A. D., and Collip, J. B.: Canad. M. A. J. 22:219 ( (Feb.) ) 1930.
Novak, Emil: J. A. M. A. 95:1225 ( (Oct. 25) ) 1930.
Gardiner-Hill and Smith: Lancet 1:464, 1931.
Morse, A. H.: Yale J. Biol. Med. 3:397 ( (May) ) 1931.
Hamblen, E. C.: Endocrinology 15:184 ( (May-June) ) 1931.
Kincaid, H. L.: Texas State J. Med. 27: 313 ( (Aug.) ) 1931.
Novak, Emil, and Hurd, G. G.: Am. J. Obst. & Gynec. 22:501 ( (Oct.) ) 1931.
Hamblen, E. C.: Virginia M. Monthly 58:509 ( (Nov.) ) 1931.
Frank, R. T.: J. A. M. A. 97:1852 ( (Dec. 19) ) 1931.
Gerhardt, L., abstr. J. A. M. A. 98:2033 ( (June 4) ) 1932.
Kurzrok, R., and Ratner, S.: Am. J. Obst. & Gynec. 23:689 ( (May) ) 1932.
Geist, S. H., and Spielman, F., Am. J. Obst. & Gynec. 23:697, 701 ( (May) ) 1932.
Hamblen, E. C.: South. M. & S. J. 94:339 ( (June) ) 1932.
Werner, A. A.: Proc. Soc. Exper. Biol. & Med. 29:1142 ( (June) ) 1932.
Hirst, J. C.: J. M. Soc. New Jersey 29:574 ( (July) ) 1932.
Kurzrok, R.: Endocrinology 16:361, 366 ( (July-Aug.) ) 1932.
Novak, Emil: South. M. J. 25:856 ( (Aug.) ) 1932.
Mazer, C., and Goldstein, L.: Clinical Endocrinology of the Female , Philadelphia, 1932.
Allen, Edgar, editor: Sex and Internal Secretions , Baltimore, Williams and Wilkins Company, 1932.
Kauffmann, C.: Zentralbl. f. Gynäk. 57:42 ( (Jan. 7) ) 1933.
Werner, A. A., and Collier, W. D.: J. A. M. A. 100:633 ( (March 4) ) 1933.
While other preparations, in particular Amniotin (Squibb), have been found in experimental and in clinical use apparently to produce effects comparable to those of the crystalline Theelin, all such products have been classed here under the generic term "estrogenic substance." This is not intended as reflection on the potency or possible usefulness of such products.
Marshall, F. H. A.: Brit. M. J. 2:232 ( (Aug. 6) ) 1932.
Dodds, E. C.: Am. J. Obst. & Gynec. 22: 520 ( (Oct.) ) 1931.
Frank, Novak and others.74
Kunde, M. M., and others: Proc. Soc. Exper. Biol. & Med. 22: 122 ( (Nov.) ) 1930
Am. J. Physiol. 95:630 ( (Dec.) ) 1930.
Haupstein, P.: Endokrinologie 8:169, 1931.
Marrian, G. F., and Parkes, A. S.: J. Physiol. 69: 372, 1930.
Novak, Emil, and Hurd, G. G.: Am. J. Obst. & Gynec. 22:501 ( (Oct.) ) 1931.
White, C. E.: J. Oklahoma M. A. 25:304 ( (July) ) 1932.
Kimm, H. T., and Van Allen, C. M.: J. A. M. A. 99:991 ( (Sept. 17) ) 1932.
Frank, R. T.: J. A. M. A 97: 1852 ( (Dec. 19) ) 1931
S. Clin. North America 12:310 ( (April) ) 1932.
Mazer, C., and Goldstein, L.: Clinical Endocrinology of the Female , Philadelphia, 1932, p. 426.

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