Study concept and design: Poets, Roberts, Schmidt, Whyte, Bairam, Nelson.
Acquisition, analysis, or interpretation of data: Roberts, Schmidt, Whyte, Asztalos, Bader, Moddemann, Peliowski, Rabi, Solimano, Nelson.
Drafting of the manuscript: Poets, Roberts, Schmidt, Whyte.
Critical revision of the manuscript for important intellectual content: Asztalos, Bader, Bairam, Moddemann, Peliowski, Rabi, Solimano, Nelson.
Statistical analysis: Roberts.
Obtained funding: Roberts, Schmidt, Whyte, Asztalos, Rabi, Solimano.
Administrative, technical, or material support: Poets, Schmidt, Whyte, Bader.
Study supervision: Poets, Roberts, Schmidt, Whyte.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Poets reports grants from Chiesi Farmaceutici SpA and Masimo. Mr Roberts and Dr Schmidt report receipt of grants from the Canadian Institutes of Health Research. Dr Rabi reports a patent with royalties paid by Masimo (this technology was not used in the current study). Mr Nelson reports receipt of a consultant fee from the Canadian Institutes of Health Research. No other disclosures were reported.
Canadian Oxygen Trial Investigators: (Study sites are listed according to the number of infants they enrolled.) Mount Sinai Hospital, Toronto, Ontario, Canada: Prakesh Shah, MSc, MBBS, MD, DCH, MRCP, FRCPC; Leanne Brown, BSc(H), RRT; Lisa Wenger, RRT/AA; Samantha Frye, BSc(H), RRT; Francesca Imbesi, HBSc, RRT; Edmond Kelly, MB, BCh, BAO, DCH, FAAP. McMaster University Medical Center, Hamilton, Ontario, Canada: Judy D’Ilario, RN; Madan Roy, MD, MBBS, MRCP, FRCPC; Barbara Schmidt, MD, MSc, FRCPC; Joanne Dix, RN, CNS; Beth Adams, PhD; Janice Cairnie, RN; Patrice Gillie, RN, BScN. Sunnybrook Health Sciences Center, Toronto, ON, Canada: Elizabeth V. Asztalos, MD, MSc, FRCPC; Marilyn Hyndman, RRT, MAppSc(Resp); Maralyn Lacy, BSc, RN; Denise Hohn, OT Reg(Ont); Laura Cooper Kruk, MSc (OT), OT Reg(Ont). Pennsylvania Hospital, Philadelphia: Soraya Abbasi, MD; Toni Mancini, RN, BSN, CCRC; Emidio Sivieri, MS.E; Kathleen Finnegan, MEd. Centre Hospitalier Universitaire de Quebec, Quebec City,Canada: Aida Bairam, MD, PhD; Sylvie Bélanger, MD, FRCPC; Marianne Deschenes, MD; Annie Fraser, MPs. The Ottawa Hospital and Children’s Hospital of Eastern Ontario, Ottawa, Canada: JoAnn Harrold, MD, FRCPC; Jane Frank, RN; Julie Barden, RN. IWK Health Centre, Halifax, Nova Scotia, Canada: Robin Whyte, MBBS, FRCPC; Michael Vincer, MD, FRCPC; Sharon Stone, RN. Foothills Medical Centre and Alberta Children’s Hospital, Calgary, Canada: Yacov Rabi, MD, FRCPC; Reg Sauve, MD, MPH, FRCPC; Danielle Cyr, BHSc; Heather Christianson, BA; Deborah Anseeuw-Deeks, BN; Dianne Creighton, PhD, RPsych. Children’s & Women’s Health Centre of British Columbia, Vancouver, Canada: Alfonso Solimano, MD, FRCPC; Lindsay Colby, BScN, RN, MSN(c); Arsalan Butt, MSc; Anne Synnes, MDCM, MHSC, FRCPC; Meredith Peterson, RRT. Hospital of the University of Pennsylvania, Philadelphia: Barbara Schmidt, MD, MSc, FRCPC; Aasma Chaudhary, BS, RRT; Hallam Hurt, MD; Danielle Foy, CRNP, MSN; Kristina Ziolkowski, CMA; Marsha Gerdes, PhD; Judy Bernbaum, MD. Royal Alexandra Hospital, Edmonton, Alberta, Canada: Abraham Peliowski, MD, FRCPC, FAAP; Manoj Kumar, MBBS, MD, MSc; Leonora Hendson, MBBCh, MSc; Melba Athaide, RN, BScN; Jill Tomlinson, CHIM. University Children’s Hospital of Tuebingen, Germany: Christian F. Poets, MD; Dirk Bassler, MD, MSc; Jutta Armbruster, RN. FUNDASAMIN, Buenos Aires, Argentina: Nestor Vain, MD; Cecilia Garcia, MD. Maternidad Suizo, Buenos Aires, Argentina: Vanesa DiGruccio, MD; Fernanda Tamanaha, MD. Sanatorio de la Trinidad, Buenos Aires, Argentina:Noemí Jacobi, MD. Sanatorio Otamendi, Buenos Aires, Argentina: Silvia Garcia, MD; Norma Vivas, MD; Cristina Osio, MD. Stony Brook University Medical Center, Stony Brook, NY: Shanthy Sridhar, MD, FAAP; Aruna Parekh, MD; Rose McGovern, RN. Meir Medical Center, Kfar-Saba, Israel: Shmuel Arnon, MD; Michelle Meyer, RN; Rachel Poller, RN. McGill University Health Centre, Montreal, Quebec, Canada: Nabeel Ali, MD, FRCPC; May Khairy, MD,CM, FRCPC; Isabelle Paquet, PhD; Larissa Perepolkin, BA; Patricia Grier, BScN; Sadia Wali, DMD. Winnipeg Health Sciences Centre, Winnipeg, Manitoba, Canada: Mary Seshia, MBChB, MRCP(UK), FRCP(Ed); Diane Moddemann, MD, MEd, FRCP, FAAP; John Minski, RRT; Valerie Cook, RN; Kim Kwiatkowski, RN; Karen A. H. Penner, MSc, BMROT; Debbie Williams, RN, BN. Royal University Hospital, Saskatoon, Saskatchewan, Canada: Laurentiu Givelichian, FRCP(C); Koravangattu Sankaran, MD, FRCP, FCCM; Cindy Thiel, MS, RN(NP), NNP-BC. Bnai Zion Medical Center, Haifa, Israel: David Bader, MD, MHH; Bella Sandler, RN. St Boniface General Hospital, Winnipeg, Manitoba, Canada: Aaron Chiu, MD, FRCPC, FAAP; Diane Moddemann, MD, MEd, FRCP, FAAP; Dayle Everatt, RCT, RN, BA; Naomi Granke, RN, CCRP. Soroka University Medical Center, Beer Sheva, Israel: Agneta Golan, MD; Esther Goldstein, PhD; Shlomith Dadoun, BN. Oulu University Hospital, Oulu, Finland: Riitta Vikevainen, RN; Hanna Kallankari, MD; Tuula Kaukola, PhD; Mikko Hallman, MD, PhD, FRCPE. Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec, Canada: Keith Barrington, MB, ChB; Julie Lavoie, RN. Steering Committee: Barbara Schmidt (chair), MD, MSc, FRCPC, McMaster University, Hamilton, Ontario, Canada, and University of Pennsylvania, Philadelphia; Elizabeth V. Asztalos, MD, MSc, FRCPC, University of Toronto, Toronto, Ontario, Canada; Christian F. Poets, MD, Eberhard Karls University, Tuebingen, Germany; Yacov Rabi, MD, University of Calgary, Calgary, Alberta, Canada; Robin S. Roberts, MSc, McMaster University, Hamilton, Ontario, Canada; Alfonso Solimano, MD, FRCPC, University of British Columbia, Vancouver, Canada; Robin K. Whyte, MBBS, FRCPC, Dalhousie University, Halifax, Nova Scotia, Canada. Bayley III Adjudication Committee: Diane Moddemann, MD, MEd, FRCP, FAAP, University of Manitoba, Winnipeg, Canada; Karen A. H. Penner, MSc, BMROT, University of Manitoba, Winnipeg, Canada. Data and Safety Monitoring Board: William Fraser (chair), MD, MSc, University of Montreal, Montreal, Quebec, Canada; Deborah J. Davis, MDCM, CSPQ, FRCPC, University of Ottawa, Ottawa, Ontario, Canada; George Wells, MSc, PhD, University of Ottawa, Ottawa, Ontario, Canada. Nurse Consultant: Judy D’Ilario, RN, McMaster University, Hamilton, Ontario, Canada. Neonatal Trials Group (Coordinating Center) at McMaster University, Hamilton, Ontario, Canada: Robin S. Roberts, MSc; Lorrie Costantini, BA; Judy D’Ilario, RN; Wendy Yacura; Bronwyn Gent; Harvey Nelson, MSc.
Funding/Support: This study was funded exclusively by Canadian Institutes of Health Research grant MCT-79217.
Role of the Funder/Sponsor: The funding agency had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.