Since its original publication in 1910, this work has been recognized as a classic textbook in pharmacology. It is constructed with the human body and its functions primarily in mind, rather than various drug substances classified either by botanic groups or by chemical composition. It begins logically with the actions of drugs on nerve endings, and proceeds through the various systems of the body to final chapters on the pharmacology of inflammatory processes, specific actions on the causes of diseases, and the mode of action of drugs. The revision of the book has taken into account the 1926 U. S. Pharmacopeia and the 1914 British Pharmacopeia, which dosages are given in the discussions. The book is marred to some extent by the inclusion of quite a few Germanic expressions.