This case is reported in view of the unusual nature of the allergin and the possibility that similar instances of hypersensitiveness may be fairly common.
Mrs. C., white, aged 23, seen Feb. 12, 1932, complained of giant urticaria since the preceding November. The lesions were from 4 to 8 inches in diameter and occurred chiefly on the face and extremities, but appeared on any part of the body. She was sometimes free for as long as two weeks; again she would have two or three attacks in twenty-four hours. At the age of 16 she had one attack after eating strawberries. She was married at 18 and had her first child at 21, and a second child eighteen months later. Labor was normal. The menses reappeared when the second child was 5 months old and were accompanied by an attack of giant hives. She also noticed local irritation during the