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Potential Adverse Effects of Anesthesia in Children

Christopher M. Ward, MD1; Kirk J. Hogan, MD, JD2; Roderic G. Eckenhoff, MD3
[+] Author Affiliations
1Department of Anesthesiology and Critical Care, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
2Department of Anesthesiology, University of Wisconsin School of Medicine and Public Health, Madison
3Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia
JAMA. 2015;314(4):408-409. doi:10.1001/jama.2015.7378.
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To the Editor In their Viewpoint, Dr Psaty and colleagues1 underscored the potential adverse effects of widely used anesthetics on the developing brain. The authors concluded: “No similar safety concerns have been raised for anesthetic agents in adults.” To the contrary, not only has this issue been raised, but it rests on a substantial body of preclinical and clinical research acquired over many decades.


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July 28, 2015
Bruce M. Psaty, MD, PhD; Richard Platt, MD, MS; Russ B. Altman, MD, PhD
1Cardiovascular Health Research Unit, University of Washington, Seattle
2Harvard Medical School, Boston, Massachusetts
3Stanford University, Stanford, California
JAMA. 2015;314(4):409. doi:10.1001/jama.2015.7387.
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