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ARTICLE |

MALARIAL THERAPY IN DEMENTIA PARALYTICA

H. R. UNSWORTH, M.D.
JAMA. 1930;95(11):772-774. doi:10.1001/jama.1930.02720110008003.
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ABSTRACT

The De Paul Sanitarium in New Orleans, an institution for the treatment of nervous and mental disorders, is advantageously situated in regard to climate and for securing malarial organisms. Rarely is it necessary to wait any prolonged period of time before obtaining the tertian type of organisms used in this work. It is also noteworthy that we get cases that are not of the usual state institutional type; that is, dilapidated patients, but also cerebrospinal syphilitic patients who are just beginning to manifest psychic symptoms of dementia paralytica and in whom serologic examination reveals early changes in the paretic zone in the colloidal gold test. On account of this wide variance in the grade of patients with dementia paralytica it has given me an opportunity to conclude distinctly that malarial therapy is undoubtedly best in these early cases and that little improvement may be expected from those in the late

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