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JAMA. 1926;86(12):887-888. doi:10.1001/jama.1926.02670380077028.
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Effect of Sugar in Intensifying the Action of Roentgen Rays on Cancer Cells  In a series of experiments with various substances and roentgen rays, Dr. E. S. Mayer succeeded in intensifying materially the action of roentgen rays by injecting intravenously, in advance, a 10 per cent solution of dextrose. Silberstein had already shown that in cancer tissue a more active metabolism of carbohydrates occurs than in normal tissue. By the administration of insulin he had brought about changes in cancer growth. At the last session of the Gesellschaft der Aerzte, Mayer presented a number of cases of cancer of the larynx in which, by use of the method outlined above, he had effected marked improvement. Not only malignant neoplasms reacted to the treatment but also benign tumors (lymphomas, fibromas) retrogressed more rapidly than otherwise. Injection of the sugar directly into the tumor tissue appears to give better results than the


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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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