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August 16, 1930, Vol 95, No. 7 >
ARTICLE | August 16, 1930

DIABETES INSIPIDUS AND OSTEITIS FIBROSA POLYCYSTICA

Abraham Sophian, M.D.
JAMA. 1930;95(7):483-484. doi:10.1001/jama.1930.27210070001010.
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In the case of diabetes insipidus here recorded, the following rare and interesting features deserve emphasis: (1) the exceedingly rare complication of an extensive osteitis fibrosa polycystica; (2) a most unusual degree of uniform pulmonary fibrosa of interesting origin.

REPORT OF CASE  A man, aged 39, American, had apparently been well until the age of 25, when an excessive thirst developed; at times the patient drank as much as 15 gallons (60 liters) of water a day with corresponding polyuria. This condition continued uncontrolled until he reported to me seven years later. With the establishment of diabetes insipidus, pituitary extract (posterior lobe) therapy was stated with complete control of the symptoms.Impotence developed shortly after the onset of the polydipsia and has continued unimproved. The patient showed steady loss of vigor, strength and weight to a total of 60 pounds (27 Kg.).An extensive generalized eczema developed early and has

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