Study concept and design: Pandya, Weinstein, Gaziano.
Acquisition, analysis, or interpretation of data: Pandya, Sy, Cho, Weinstein, Gaziano.
Drafting of the manuscript: Pandya, Cho, Gaziano.
Critical revision of the manuscript for important intellectual content: Pandya, Sy, Weinstein, Gaziano.
Statistical analysis: Pandya, Sy, Weinstein, Gaziano.
Obtained funding: Gaziano.
Administrative, technical, or material support: Cho, Weinstein, Gaziano.
Study supervision: Pandya, Gaziano.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Pandya reports receiving grant funding from the National Institutes of Health (NIH) and the American Heart Association. Dr Weinstein reports receiving grant funding from the NIH and personal fees from Optuminsight. Dr Gaziano reports receiving grant funding from the NIH. No other disclosures were reported.
Funding/Support: This work is supported by grant 5R01HL104284-03 to the Harvard School of Public Health from the National Heart, Lung, and Blood Institute (Dr Gaziano).
Role of the Funder/Sponsor: The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or the decision to submit the manuscript for publication.
Article Correction: This article was corrected for incorrect data in the Abstract and Conclusion on August 10, 2015.