In this course of general lectures, first the normal structure of nervous tissue is analyzed, and then pathologic alterations are considered. The author writes: "Any one familiar with the subject will easily recognize the influence of the investigations of Nissl upon the treatment of the material and the selection of the themes. Nissl's researches form the foundation of a large part of the entire presentation." In reading the text this acknowledgment of indebtedness to Nissl should be borne in mind, for it is the source at the same time of the greatest strength of the work and also of certain limitations. The description of the nervous elements in the first three chapters is a lucid presentation of Nissl's well known views in very compact form. Also, the researches of Apathy, Bethe and others are summarized. Naturally, from this point of view, the neuron doctrine is subjected to rather severe arraignment.