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Comment & Response |

Discordant Interpretations of Breast Biopsy Specimens by Pathologists

George Leonard, MD, PhD1
[+] Author Affiliations
1Madigan Army Medical Center, Tacoma, Washington
JAMA. 2015;314(1):82-83. doi:10.1001/jama.2015.6224.
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To the Editor I was one of the pathologists who participated in the study by Dr Elmore and colleagues.1 Although the conclusions are appropriately measured based on the inherent constraints imposed by the design, I have significant misgivings about the validity of the study based on my personal experience.

My participation was contingent on the promise of receiving relevant feedback to improve my practice. The recruitment material stated the purpose of the study was to “identify ways in which we can improve breast cancer diagnosis.” A single slide is certainly not the way I or most other pathologists practice. The investigators stated that there would be scheduled slides to review on a regular basis.


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July 7, 2015
Joann G. Elmore, MD, MPH; Margaret S. Pepe, PhD; Donald L. Weaver, MD
1University of Washington School of Medicine, Seattle
2Fred Hutchinson Cancer Research Center, Seattle
3University of Vermont School of Medicine, Burlington
JAMA. 2015;314(1):83-84. doi:10.1001/jama.2015.6239.
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