Physicians will welcome the new edition of this standard and scholarly book. The author has devoted more than twenty-five years to intensive study and research in the field of the endocrine glands. The exposition of the physiology and pathology of the ductless glands is comprehensive, clear and thorough, and his conclusions are rational when conflicting views of uncertain relationships are dealt with. The present edition contains much new matter, especially in the chapter on the pancreas and the chapter on the reproductive organs. The number of illustrations has been increased from 105 to 112, and a short chapter on organotherapy has been added to the book. The portions dealing with clinical subjects have been still further expanded, and this will make the book still more useful to medical students and practitioners.