JAMA. 1925;85(18):1382-1385. doi:10.1001/jama.1925.02670180038010.
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The old idea that chronic gastric ulcer occurs with much greater frequency than chronic duodenal ulcer has been abandoned since clinicians (especially surgeons) awakened the attention of pathologists to the frequency of the latter lesion. In 1833, the relative proportion of gastric ulcers to duodenal ulcers in necropsy reports was 39: 1; in 1870, it became 12: 1; in 1913, in Berlin statistics, it had fallen to 1: 1. These differences in reported incidence at necropsies appear to have been due partly to negligence of close examination of the duodenum in the earlier periods, partly (before the criteria for recognition of the boundary line between pylorus and duodenum had been established) to the assumption that juxtapyloric ulcers were all of gastric origin. The view, too, that gastric ulcer occurs much more often in women than in men and duodenal ulcer more often in men than in women, has given way


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