The first part of this volume presents an elaborate discussion of the Wassermann test. It goes into the details of the history and technic of complement fixation, as elaborated by Bordet and Gengou, of the original Wassermann test and of many of its modifications. The Kolmer modification is not mentioned. In summarizing this section, the author says: "Wassermann's technic remains to this day—I shall not say in an honorable position—but still in a dominant position." No mention is made of the Kahn test or any of the advances in the serum diagnosis of syphilis along the lines of precipitation. The remaining part of the volume is devoted to the clinical application of the Wassermann reaction both with serum and with spinal fluid.