The second volume of this exhaustive work is devoted to the clinical aspects of the therapeutics of the various arsenicals. The technic, indications and results of intraspinal therapy are treated at length in the first chapter. The next covers the subject of arsphenamin in hereditary syphilis, and the third that of the exanthems and icterus occuring in the course of arsphenamin therapy. Short chapters are devoted to various arsphenamins. The bibliographies appended to each chapter will be found of great value to those interested in the subjects covered.