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ARTICLE | December 15, 1923

THE TRANSMISSION OF ARSENIC FROM MOTHER TO FETUS

FRANK P. UNDERHILL, Ph.D.; FRANK G. AMATRUDA, M.D.

JAMA. 1923;81(24):2009-2012. doi:10.1001/jama.1923.02650240013004.

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The earliest record found on the antenatal treatment of congenital syphilis was that of Bertin¹ in 1810. Lancercaux,¹ in 1868, admitted that, in his opinion, antenatal treatment was the correct method of procedure; but there still existed, at that time, a well recognized school which taught that it was both wrong and dangerous. The treatment at that time consisted in the administration of mercury in some form plus the free use of potassium iodid. This method of treatment had only a slight degree of success. Since the introduction of arsphenamin, the antenatal treatment of congenital syphilis with arsenic and mercury has had a surprising degree of success. Greenlees² and Findlay³ report complete success in their series of cases, which, although few in number (fifteen), contained some that have been followed for a period of seven years. Fordyce and Rosen⁴ have obtained excellent results after adequate

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Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

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UNDERHILL FP, AMATRUDA FG. THE TRANSMISSION OF ARSENIC FROM MOTHER TO FETUS. JAMA. 1923;81(24):2009-2012. doi:10.1001/jama.1923.02650240013004.

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