0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
ARTICLE |

IMMUNIZATION OF ANTHROPOID APES AGAINST TUBERCULOSIS

JAMA. 1925;85(11):826-827. doi:10.1001/jama.1925.02670110040013.
Text Size: A A A
Published online

The first detailed report of a long projected experiment on the vaccination of monkeys against tuberculosis in their native environment has recently been published. From time to time1 there have appeared in French medical literature accounts of research on the immunizing power of a bacillary vaccine, prepared by Calmette and Guérin, and called for simplicity BCG. This vaccine consists of tubercle bacilli greatly reduced in virulence by prolonged cultivation on potato or agar saturated with bile containing 5 per cent. glycerol. Calmette and Guérin have repeatedly asserted that this vaccine confers immunity without producing anatomic tubercle. According to Calmette,2 the only effect of massive injection of this bacillus is "general disease which is like typhoid fever and which cures itself spontaneously after fifteen to twenty days without producing the slightest tubercle formation." Yet calves, guinea-pigs, rabbits and monkeys treated with doses of a few milligrams of the substance,

Topics

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();