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AGGLUTINATION OF TYPHOID GROUP OF ORGANISMS IN CASES OF JAUNDICE AMONG VACCINATED PERSONS

HENRY J. NICHOLS, M.D.
JAMA. 1923;81(23):1946-1948. doi:10.1001/jama.1923.02650230030009.
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In recent years an unusual number of cases of jaundice, sometimes in epidemics, have come under the care of American physicians, especially in the Northeastern states. The most recent report is that by Bloomer,1 which expresses the current opinion that the disease is an infection due to some specific organism at present unknown. The same increase in cases of jaundice has been reflected in the army, without, however, the occurrence of any definite epidemics, so far as I know. Sporadic cases have occurred in a number of stations in the Second Corps Area, which includes New York, New Jersey and Delaware. In the course of an investigation of this disease, one positive finding has been made, which, it is thought, should be recorded.

A number of cases have shown, in the blood serum, a definite agglutination of paratyphoid B bacilli, with a less marked agglutination of typhoid and paratyphoid

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