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JAMA. 1923;80(23):1694-1695. doi:10.1001/jama.1923.02640500036014.
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"The old notion of 'diathetic diseases' is now giving place to the more definite concept of disorders of metabolism, many, perhaps all, of which are bound up with some bouleversement of hormonic equilibrium or some disturbance of function in the ductless glands."1 Laboratory research and experimentation are making this pronouncement of Dr. Fielding H. Garrison, medical historian, more evident each day; but the regrettable fact remains that our prophylaxis does not altogether keep step with our knowledge. The studies of Marine and Kimball with regard to simple goiter, which were made possible under research grants from the American Medical Association, emphasize the prevalence of simple goiter and point to a method of prevention. Hypertrophy of the thyroid has been recognized from early centuries as a definite disease. Aëtius of Amida, who lived in Byzantium in the sixth century A. D., gives an interesting chapter on goiter in his book


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