This is an excellent review of the present status of our knowledge of the septic infections in internal medicine. It is intended for those making a special study of the laboratory phases of these diseases but it is also of interest to the general practitioner. The book gives a combined picture of the etiology, pathology and clinical aspects of the treatment of septic infections. The chapter on blood cultures is complete and the interpretation of the cultures derived is well stated. The authors believe that Streptococcus hemolyticus and Streptococcusviridans may be changed to each other under suitable conditions. The defense mechanism of the human body is well presented. The various clinical pictures of sepsis are given in full detail and the chapter on agranulocytosis is excellent. There is nothing new suggested for treatment. The outlook is still quite hopeless.