Have spermatozoa any function aside from that of the propagation of the race? is a question that has arisen because of some recent experiments. Guyer1 showed that when male rabbits and guinea-pigs are injected intravenously with specific spermotoxic serums prepared from fowls, or with spermatozoa directly, sterility results, and the serum of the animal becomes spermotoxic. When the spermatozoa are injected intravenously, according to Tsukahara,2 they may cause severe toxic reactions and even death, male animals being more sensitive, and pregnant females more so than nonpregnant.
McCartney3 did not use spermotoxic serums, as did both Dittler4 and Guyer, but spermatozoa suspensions directly. In a series of seventy-nine female rats subcutaneously injected with doses of the spermatozoa suspension up to a total of 3 c.c., each cubic centimeter containing 80,000 spermatozoa, he found that the rats remained sterile for a period of from two to twenty-two weeks