About ten years ago I became interested in the study of renal tuberculosis because it seemed to me that in some way we should be able to arrest this condition before the kidney is destroyed and before the bladder becomes so impaired that it causes chronic invalidism. The hope that I might learn something about the early lesion of renal tuberculosis encouraged me to begin this clinical and pathologic study in the Hennepin County Sanatorium at Glen Lake, Minn.
Among the patients in the sanatorium I observed many who had proved urinary tuberculosis but in whom symptoms and clinical observations were either absent or not at all typical of this disease as it occurs in the practice of any urologist. This apparent difference in types of cases aroused the interest of my colleagues and myself and caused us to continue our clinical investigation.
When I studied the patient's condition during